Currently the most important prognostic factor in lung cancer is the stage. In the current lung TNM classification system, N category is defined exclusively by anatomic nodal location though, in other type of tumours, number of lymph nodes is confirmed to be a fundamental prognostic factor. Therefore we evaluated the number of mediastinal lymph nodes as a prognostic factor in locally advanced NSCLC after multimodality treatment, observing a significant effect of the number of lymph nodes in terms of OS (p<0.01) and DFS (p<0.001): patients with a low number of positive mediastinal nodes have a better prognosis.

Number of mediastinal lymph nodes as a prognostic factor in PN2 non small cell lung cancer: A single centre experience and review of the literature

Simione, L.;
2014-01-01

Abstract

Currently the most important prognostic factor in lung cancer is the stage. In the current lung TNM classification system, N category is defined exclusively by anatomic nodal location though, in other type of tumours, number of lymph nodes is confirmed to be a fundamental prognostic factor. Therefore we evaluated the number of mediastinal lymph nodes as a prognostic factor in locally advanced NSCLC after multimodality treatment, observing a significant effect of the number of lymph nodes in terms of OS (p<0.01) and DFS (p<0.001): patients with a low number of positive mediastinal nodes have a better prognosis.
2014
adult
aged
cancer staging
Carcinoma, Non-Small-Cell Lung
clinical trial
female
follow up
human
literature
Lung Neoplasms
lymph node metastasis
male
Mediastinal Neoplasms
middle aged
mortality
multimodality cancer therapy
pathology
prognosis
retrospective study
secondary
survival rate
very elderly, Adult
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung
Combined Modality Therapy
Female
Follow-Up Studies
Humans
Lung Neoplasms
Lymphatic Metastasis
Male
Mediastinal Neoplasms
Middle Aged
Neoplasm Staging
Prognosis
Retrospective Studies
Review Literature as Topic
Survival Rate
Locally advanced NSCLC
Number of lymph nodes
Prognosis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14090/3243
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